In the case of SARS-COV-2, vROs are composed of double-membrane vesicles (DMVs) that originate upon remodelling of the membranes of the endoplasmic reticulum (ER) (Fig. 1). The biogenesis of the vROs ...
The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...
Flaviviruses strategically utilize the endoplasmic reticulum (ER) in their replication cycles. However, the role of ER autophagy (ER-phagy) in viral replication process remains poorly understood. Here ...
Researchers at Umeå University have identified two human cell proteins, NUP98 and NUP153, that play a crucial role in how viruses such as tick-borne encephalitis virus (TBEV), West Nile virus, and ...
Chinese scientists uncover how the Nipah virus hijacks a host protein (NSUN2) to boost its replication through a dual mechanism, simultaneously stabilizing viral RNA and modifying a key viral protein, ...
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