Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a ...

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

Microscope image of human epithelium cells (blue) infected with SARS-CoV-2 (red), showing the virus spreading from one cell to another. LA JOLLA, CA—Despite vaccines and treatments, SARS-CoV-2—the ...

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

Scientists Uncover Shared Molecular Dependency Across Human Coronaviruses, From SARS To The Common Cold In A Nutshell Coronaviruses trigger the body’s own stress responses to chemically reprogram ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Researchers from the Institute for Basic Science of Korea and collaborating institutions have designed a new class of peptide-based inhibitors targeting a crucial interface within the SARS-CoV-2 ...