New findings reveal how the gene HNRNPU coordinates several fundamental molecular processes during the earliest stages of human brain development.
When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits that RNA before it is translated into protein. Many genes can be processed and ...
Dr. Anczukow is a leading cancer biologist with expertise in RNA biology, molecular and cell biology, as well as human genetics, cancer biology, and genomics Olga Anczukow, Ph.D. Olga Anczukow, Ph.D.
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
Pharmaceutical Technology on MSN
RNA-targeting small molecules: A new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...
Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...
v. 1. Synthesis and purification of RNA substrates / Benoit Chabot -- Characterization of RNA / Paula J. Grabowski -- Splicing of mRNA precursors in mammalian cells / Ian C. Eperon, Adrian R. Krainer ...
Phase separation in nuclear cell biology represents a conceptual framework for understanding how cells spatially and temporally regulate gene expression.
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...
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