For the first time, researchers have successfully used computational simulations to modify an enzyme’s structure to increase the optimum temperature of a reaction. Researchers at Uppsala University ...

Enzymes evolved to efficiently operate in low-temperature environments via key substitutions of amino acids in their active site, which lowers the activation energy of catalytic reactions. Life has ...

Andrew T. Nottingham, Benjamin L. Turner, Jeanette Whitaker, Nick Ostle, Richard D. Bardgett, Niall P. McNamara, Norma Salinas, Patrick Meir https://www.jstor.org ...

Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The findings ...

Enzymes from cold-loving organisms that live at low temperatures, close to the freezing point of water, display highly distinctive properties. Scientists have now used large-scale computations to ...

This accurate thermosensation relies on the precise maintenance of thermal receptor functions; however, their activation and regulatory mechanisms have remained unclear. In a new study, researchers ...