BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...

The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

Birth order, a non-genetic factor, may influence early neurodevelopment. A nationwide Japanese birth cohort study based on sibling pairs suggests that differences in neurodevelopment emerge during the ...

In a nationwide cohort study in Taiwan, positive associations between maternal acetaminophen prescriptions during pregnancy and attention-deficit/hyperactivity disorder (ADHD) and autism spectrum ...

Different approaches to cohort study design in the context of biomarkers of aging. Biomarkers of aging are commonly validated using cross-sectional or longitudinal study designs. Cross-sectional ...

Objective Unplanned hospital readmissions within 30 days of discharge measure the quality of healthcare. This study aims to ...

As previously presented, gedatolisib + palbociclib + fulvestrant ('gedatolisib triplet”) and gedatolisib + fulvestrant ('gedatolisib doublet”) reduced the risk of disease progression or death versus ...

Objectives This study aimed to determine whether certain lifestyle factors, specifically alcohol consumption, smoking, physical activity, sleep duration and sleep quality, are associated with an ...