Purpose: Single genetic variants in multifactorial disorders typically have small effects, so major increases in disease risk are expected only from the simultaneous exposure to multiple risk ...
In our model, individuals are autopolyploid with either four (Y 4) or six (Y 6) sets of chromosomes (that is, 2n=4x=tetraploid; 2n=6x=hexaploid), but all populations must have the same ploidy level ...
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